A multicenter prospective comparative study of 19G Fine Needle Aspiration (FNA) and Fine Needle Biopsy (FNB) needles for mediastinal and intraperitoneal lymphadenopathy

A multicenter prospective comparative study of 19G Fine Needle Aspiration (FNA) and Fine Needle Biopsy (FNB) needles for mediastinal and intraperitoneal lymphadenopathy - Prospective comparison of 19G FNA and FNB needles in the diagnosis of lymphoma

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000060703

Enrollment

160

Registered

2026-02-18

Start date

2026-02-18

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

mediastinal or abdominal lymphadenopathy

Interventions

19G FNA needle 19G FNB needle

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Cases with mediastinal or abdominal lymphadenopathy detected by CT or ultrasound imaging. 2. Cases with lymphadenopathy without a pathological diagnosis. 3. Patients aged 18 years or older. 4. Lymphadenopathy of 10mm or greater. 5. Patients not taking oral anticoagulants.

Exclusion criteria

Exclusion criteria: 1. Cases in which a pathological diagnosis of lymph node swelling has already been made 2. Cases in which endoscopic examination is difficult 3. Cases in which consent to participate in this study cannot be obtained 4. Other cases in which this study is considered medically inappropriate

Design outcomes

Primary

Measure	Time frame
Accuracy of histopathological examination: Non-inferiority of 19G FNA needle to 19G FNB needle	—

Secondary

Measure	Time frame
Pathological cytological accuracy Sensitivity of immunohistochemical staining in malignant lymphoma Sensitivity of surface markers in malignant lymphoma Sensitivity of chromosome testing in malignant lymphoma Sensitivity of FISH in malignant lymphoma	—

Countries

Japan

Contacts

Public ContactMitsuru Okuno

Matsunami General Hospital Gastroenterology

mkobdkl@yahoo.co.jp0583880111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026