Pediatric Cancer
Conditions
Interventions
Orchiectomy or partial orchiectomy will be performed under general anesthesia.
Sponsors
The University of Osaka
Eligibility
Sex/Gender
Male
Inclusion criteria
Inclusion criteria: Male patients scheduled to undergo cancer treatment that may impair spermatogenesis. Male patients from birth to prepubertal stage with bilaterally descended testes. Male patients with sufficient testicular volume to allow tissue harvesting. Male patients deemed fit to undergo general anesthesia and orchiectomy or partial orchiectomy, as determined by the Department of Anesthesiology. Male patients for whom the primary treating department has reviewed the potential impact of study participation on treatment of the underlying disease and has approved participation in this study. Male patients for whom written informed consent has been obtained. Male patients considered appropriate for participation by the principal investigator or sub-investigators.
Exclusion criteria
Exclusion criteria: Male patients without bilaterally descended testes. Male patients with known testicular abnormalities. Male patients with insufficient testicular volume for tissue harvesting. Male patients capable of ejaculation. Male patients in whom spermatozoa are present in the testes. Male patients deemed unfit to undergo general anesthesia and orchiectomy or partial orchiectomy. Male patients considered inappropriate for anesthesia by the Department of Anesthesiology. Male patients for whom participation in this study is considered to have a significant negative impact on treatment of the underlying disease and is not approved by the primary treating department. Male patients for whom written informed consent cannot be obtained. Male patients considered inappropriate for participation by the principal investigator or sub-investigators.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Success rate of testicular tissue harvesting and cryopreservation | — |
Countries
Japan
Contacts
Public ContactKentaro Takezawa
The University of Osaka Graduate School of Medicine Department of Urology
Outcome results
None listed