Middle-aged and elderly female patients with moderate to severe knee osteoarthritis symptoms and basic mobility.
Conditions
Interventions
Slow Eccentric Training (SET) Group: Participants will perform resistance training focused on eccentric muscle contractions along the myofascial chains (superficial front, back, and lateral lines). Tr
Sponsors
Qufu Normal University
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: Female participants aged between 50 and 70 years. Clinically diagnosed with knee osteoarthritis (KOA) according to the American College of Rheumatology (ACR) criteria. Radiographic evidence of tibiofemoral osteophytes on X ray imaging. Experiencing knee joint pain on most days within the past month. Numeric Rating Scale (NRS) score for knee pain >= 4 in the past week. Able to understand study instructions and provide written informed consent. Physically able to participate in supervised resistance training.
Exclusion criteria
Exclusion criteria: History of knee replacement surgery or scheduled for knee surgery during the study period. Diagnosed with rheumatoid arthritis, gout, or other forms of inflammatory joint disease. Severe cardiovascular, respiratory, neurological, or musculoskeletal disorders that may affect exercise tolerance. Current use of corticosteroid injections or intra-articular hyaluronic acid within the past 3 months. Body Mass Index (BMI) >= 35 Engaged in structured resistance training in the past 6 months. Cognitive impairment, mental illness, or inability to follow instructions. Participation in another clinical trial concurrently.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change in WOMAC pain subscale score from baseline to 12 weeks, assessed using the simplified Chinese version of the WOMAC (Western Ontario and McMaster Universities Osteoarthritis Index) scale (version 3.1). Pain is rated on a 5-point Likert scale (0 to 4) across five items, with a total score range of 0 to 20. A reduction in the score indicates improvement. | — |
Countries
Asia(except Japan)
Contacts
Public ContactPing Liu
Qufu Normal University College of Physical Education and Sport Science
Outcome results
None listed