Study on the immunological mechanisms of tranexamic acid induced anaphylaxis

Study on the immunological mechanisms of tranexamic acid induced anaphylaxis - Immunological analysis of tranexamic acid induced anaphylaxis

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000060643

Enrollment

Registered

2026-04-01

Start date

2026-04-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Tranexamic acid induced anaphylaxis

Interventions

Intradermal testing and blood sampling for immunological assessment (patient) Intradermal testing and blood sampling for immunological assessment (healthy controls)

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: One patient with a confirmed diagnosis of tranexamic acid induced anaphylaxis. Approximately five healthy individuals with prior exposure to tranexamic acid who did not experience any allergic reactions and who met the following criteria. Not taking antihistamines or corticosteroids on a regular basis No history of severe skin disease

Exclusion criteria

Exclusion criteria: None

Design outcomes

Primary

Measure	Time frame
Presence or absence of immunological responses related to tranexamic acid	—

Secondary

Measure	Time frame
Differences in immunological reactivity between healthy subjects and patients with a history of anaphylaxis	—

Countries

Japan

Contacts

Public ContactYasuhiro Amano

Nagoya University Hospital Department of Anesthesiology

amano.yasuhiro.f1@f.mail.nagoya-u.ac.jp052-744-2340

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026