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Effects of High-Frequency Transcutaneous Auricular Vagus Nerve Stimulation on SEP and PPI

Effects of High-Frequency Transcutaneous Auricular Vagus Nerve Stimulation on SEP and PPI - Effects of High-Frequency Transcutaneous Auricular Vagus Nerve Stimulation on SEP and PPI

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000060628
Enrollment
40
Registered
2026-02-09
Start date
2026-02-09
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy adults

Interventions

Transcutaneous Vagus Nerve Stimulation,Elctroencephalogram sham Stimulation

Sponsors

Niigata University of Health and Welfare
Lead Sponsor

Eligibility

Sex/Gender
Male

Inclusion criteria

Inclusion criteria: healthy adult Pain that has persisted for more than three months

Exclusion criteria

Exclusion criteria: Skin disorders, neurological disorders,

Design outcomes

Primary

MeasureTime frame
The experiment involves administering transcutaneous auricular vagus nerve stimulation to participants, measuring SEP and PPI before and after stimulation, and investigating the effects on inhibitory responses. Since vagus nerve stimulation is suggested to promote parasympathetic dominance and potentially reduce pain, it can clarify the effects on neural inhibitory function in chronic pain patients.

Countries

Japan

Contacts

Public ContactKoya Yamashiro

Niigata University of Health and Welfare Department of Health and Sports

yamashiro@nuhw.ac.jp025-257-4757

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026