Major Depressive Disorder, Persistent Depressive Disorder, Panic Disorder, Agoraphobia, Social Anxiety Disorder, Obsessive-Compulsive Disorder, Generalized Anxiety Disorder
Conditions
Interventions
The Group Cognitive Behavioral Therapy Based on the Unified Protocol
Sponsors
National Center of Neurology and Psychiatry
Musashino University Japan Depression Center Rokubancho mental clinic Rikkyo University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) Individuals who meet the DSM-5 diagnostic criteria at the pre-intervention assessment for one of the following: major depressive disorder, persistent depressive disorder, panic disorder, agoraphobia, social anxiety disorder, obsessive-compulsive disorder, or generalized anxiety disorder 2) Moderate or greater symptom severity (Clinical Global Impressions-Severity of Illness: CGI-S >= 4) is present at the pre-intervention assessment, as assessed by the CGI-S 3) Age between 18 and 70 years 4) Individuals who are deemed by the treating psychiatrist to be suitable for CBT 5) Individuals who provided written informed consent after understanding the purpose and procedures of the study and agreeing to participate voluntarily
Exclusion criteria
Exclusion criteria: 1) Individuals with alcohol use disorder or substance use disorder at the pre-intervention assessment 2) Individuals with hypomanic episodes, manic episodes, or psychotic disorders at the pre-intervention assessment 3) Individuals who exhibit marked suicidal ideation (rated as severe on the Suicide module of the GRID-HAMD) at the pre-intervention assessment 4) Individuals who are known in advance to have difficulty attending six or more sessions during the intervention period 5) Individuals who are receiving other structured psychotherapies (excluding supportive therapy and psychoeducation) during the intervention period 6) Individuals who, at the pre-intervention assessment, have physical illnesses or severe cognitive impairment to a degree that would make it difficult to carry out the group-based UP 7) Individuals deemed unsuitable for participation in this study by the principal investigator
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Feasibility: dropout rates, intervention satisfaction (CSQ-8), adverse events Efficacy: clinical global impression-severity (CGI-S) | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Assessment of Diagnosed Mental Disorders (DIAMOND) 2. Clinical global impression-improvement (CGI-I) 3. Objective severity of depressive symptoms (GRID-HAMD) 4. Subjective severity of depressive symptoms (PHQ-9, ODSIS) 5. Subjective severity of anxiety symptoms (GAD-7, OASIS) 6. Transdiagnostic dimensions of emotional disorders (MEDI) 7. Social functioning (WSAS) 8. Quality of Life (EuroQol) 9. Subjective change of positive emotions (PES) 10. Subjective change of other emotions (OES) 11. Group alliance (GSRS) 12. Working alliance (J-WAI-SR) 13. Group cohesion (GCS) 14. Adherence to Homework (HCS) | — |
Countries
Japan
Contacts
Public ContactNoriko Kato
National Center of Neurology and Psychiatry National Center for Cognitive Behavior Therapy and Research
Outcome results
None listed