A prospective observational study to clarify the usefulness of bronchial lavage in patients with anti-GPL-core IgA antibody-positive pulmonary nontuberculous mycobacterial disease

A prospective observational study to clarify the usefulness of bronchial lavage in patients with anti-GPL-core IgA antibody-positive pulmonary nontuberculous mycobacterial disease - A prospective observational study to clarify the usefulness of bronchial lavage in patients with anti-GPL-core IgA antibody-positive pulmonary nontuberculous mycobacterial disease

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000060591

Enrollment

Registered

2026-02-05

Start date

2026-01-26

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pulmonary infection due to non-tuberculous mycobacterium

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: (a) Patients eligible for bronchoscopy (b) Patients undergoing elective bronchoscopy (c) Patients with a performance status of 2 or less (d) Patients with written consent (e) Patients aged 20 years or older (regardless of gender) (f) Patients with positive MAC antibodies (qualitative mycobacterial antibodies) (GPL core IgA antibody: MAC antibody 0.7 U/mL or higher)

Exclusion criteria

Exclusion criteria: (a) Patients with contraindications for bronchoscopy (b) Patients with mental conditions that make it difficult to participate in a clinical trial (C) Patients who are otherwise deemed inappropriate for enrollment in this study by a physician

Design outcomes

Primary

Measure	Time frame
Diagnostic rate of BL for NTM: Percentage of BL culture positive cases in MAC antibody (qualitative acid-fast bacillary antibody) positive cases (GPL core IgA antibody: MAC antibody 0.7 U/mL or higher)	—

Countries

Japan

Contacts

Public ContactDAISUKE MINAMI

Himeji Saint Mary's Hospital Department of Respiratory Medicine

d-minami@bj8.so-net.ne.jp0792655111

Outcome results