Hydrogen-releasing bath salts for post-exercise recovery (temperature, muscle oxygenation, and oxidative stress): a single-blind crossover pilot study

Randomized single-blind counterbalanced crossover pilot trial comparing hydrogen-releasing bath salts (Vitalise Bath) versus warm-water control on oxidative stress (d-ROMs, BAP), thermoregulation, and muscle oxygenation after exercise - H2Bath Crossover Recovery Study

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000060564

Enrollment

Registered

2026-02-03

Start date

2023-07-25

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Post-exercise fatigue and recovery (recovery with warm-water immersion)

Interventions

hydrogen-releasing bath salts dissolved warm water

Eligibility

Sex/Gender

Male

Inclusion criteria

Inclusion criteria: Healthy males aged from 20 to 29 years Able to provide written informed consent Able to attend both sessions (crossover)

Exclusion criteria

Exclusion criteria: History or current treatment of cardiovascular/respiratory/metabolic diseases Acute illness/fever, skin disease, or contraindication to hot bathing (e.g., heat intolerance/syncope) Deemed inappropriate by the investigator

Design outcomes

Primary

Measure	Time frame
Deep muscle temperature of the quadriceps (vastus lateralis): recovery time-course (baseline pre-bath, during 20-min bath, and 20-min post-bath recovery)	—

Secondary

Measure	Time frame
Sublingual temperature: time-course (baseline pre-bath, during 20-min bath, and 20-min recovery) Muscle oxygenation (NIRS, O2Hb): time-course (baseline, during bath, recovery) d-ROMs: pre- and post-bath (pre/post) BAP: pre- and post-bath (pre/post)	—

Countries

Japan

Contacts

Public ContactPengyu Deng

Venex Co., Inc. Research and Development Group

to@venex-j.co.jp0462009288

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026