Chronic Kidney Disease (CKD)
Conditions
Interventions
None listed
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Eligible participants are adult patients (>=18 years old) with chronic kidney disease, regardless of sex, who are judged by the principal or co-investigators to fulfill all of the following criteria: Diagnosed with a major renal disease such as diabetic kidney disease, nephrosclerosis, or IgA nephropathy. Kidney biopsy specimens have been appropriately fixed and preserved, allowing for immunohistochemical assessment. Clinical laboratory data are documented in the electronic medical records.
Exclusion criteria
Exclusion criteria: Cases where immunohistochemical evaluation is not feasible due to insufficient biopsy specimen quantity or inadequate preservation. Cases with significant gaps in follow-up data that prevent assessment of renal function progression. Cases with an unconfirmed or unclassifiable histopathological diagnosis (cases potentially requiring future re-evaluation of kidney biopsy findings are excluded from this study).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Association between expression levels of glucose metabolism-related molecules by immunostaining, fibrosis indices, and eGFR slope | — |
Countries
Japan
Contacts
Saitama Medical University Hospital Department of Nephrology