Analysis of lower limb muscle oxygenation kinetics during upper limb exercise in wheelchair users

Analysis of lower limb muscle oxygenation kinetics during upper limb exercise in wheelchair users - Analysis of lower limb muscle oxygenation kinetics during upper limb exercise in wheelchair users

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000060453

Enrollment

Registered

2026-01-23

Start date

2026-01-23

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Spinal cord injury, Spina bifida, Lower limb amputation, Healthy participants

Interventions

Cardiopulmonary exercise testing Wheelchair propulsion exercise

Eligibility

Sex/Gender

Male

Inclusion criteria

Inclusion criteria: Wheelchair User Group Adult males who are habitual wheelchair users due to conditions such as spinal cord injury (cervical or thoracolumbar), spina bifida, or lower limb amputation. Individuals capable of safely performing voluntary exercise using an upper limb ergometer. Individuals who demonstrated a full understanding of participation in this study and provided written informed consent. Healthy Control Group Healthy males matched to the wheelchair user group for age and sex. Individuals with no history of neurological or orthopedic disorders affecting lower limb motor function. Individuals who demonstrated a full understanding of participation in this study and provided written informed consent.

Exclusion criteria

Exclusion criteria: Individuals with acute or uncontrolled cardiovascular diseases (e.g., heart failure, arrhythmia, angina pectoris). Individuals with severe respiratory diseases. Individuals with marked autonomic dysfunction presenting a high risk of exercise-induced hypotension or syncope. Individuals unable to safely perform arm crank exercise due to severe contracture, pain, or orthopedic disorders in the upper limbs. Individuals unable to understand the study, provide informed consent, or adhere to instructions due to cognitive impairment or psychiatric disorders. Individuals deemed unsuitable for participation by a physician for safety reasons.

Design outcomes

Primary

Measure	Time frame
Changes in lower limb muscle oxygenation kinetics during upper limb exercise testing	—

Secondary

Measure	Time frame
Muscle oxygenation kinetics, Cerebral oxygenation kinetics, Hemodynamic parameters, Respiratory gas analysis, Exercise tolerance indices, Physical characteristics	—

Countries

Japan

Contacts

Public ContactYasuhiro Endo

Fukushima Medical University Department of Physical Therapy

ysendo@fmu.ac.jp024-581-5539

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026