A study investigating how different pain relief methods after total knee replacement surgery affect pain and ease of movement

Effects of different peripheral nerve block techniques on postoperative pain and motor function after total knee arthroplasty - PNB-TKA Study

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000060438

Enrollment

Registered

2026-01-26

Start date

2026-01-26

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Osteoarthritis of the Knee

Interventions

Patients undergoing bilateral total knee arthroplasty were randomly assigned to either a continuous femoral nerve block group or a continuous adductor canal block group. Begin continuous infusion of 0

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients undergoing bilateral simultaneous total knee arthroplasty for bilateral osteoarthritis of the knee.

Exclusion criteria

Exclusion criteria: Patients with rheumatoid arthritis, patients with a history of neuromuscular disease, patients whose preoperative walking ability requires a wheelchair.

Design outcomes

Primary

Measure	Time frame
The primary outcome measures are pain, number of additional analgesic doses administered, quadriceps strength measured using the Q-setting, date of first successful active leg raise, and date of first successful single-leg stance with upper limb support. Pain and quadriceps strength using the Q-setting will be assessed on postoperative days 1, 3, 5, and 7.	—

Countries

Japan

Contacts

Public ContactNaoyuki Kubo

Fukui General Hospital Department of Rehabilitation

fsmsc@f-gh.jp0776-59-1300

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026