None listed
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.Female participants aged 35 to 59 years. 2.Individuals who have previously experienced discomfort or adverse skin reactions to skincare cosmetics (*) and consequently discontinued their use. *Examples include skin redness, stinging or tingling sensations, or acne formation. 3.Individuals who are concerned about wrinkles around the outer corners of the eyes (crow's feet). 4. Individuals who are not currently using any facial serum (beauty essence).
Exclusion criteria
Exclusion criteria: 1.Individuals who have skin conditions such as atopic dermatitis or other dermatological symptoms on the test area (face). 2.Individuals who are pregnant or may be pregnant at the time of obtaining nformed consent. 3.Individuals who are breastfeeding or plan to breastfeed during the study period. 4.Individuals who are currently visiting a medical institution due to poor hysical condition or skin disease at the time of recruitment. 5.Individuals who have severe allergies (e.g., hay fever or rhinitis) that may affect the study results. 6.Individuals who regularly take prescription or over-the-counter medications including antibiotics, anti-inflammatory drugs, anti-allergy drugs, sleeping pills, analgesics, hormonal agents, laxatives, or intestinal regulators). Occasional use, about once or twice a month, is acceptable. 7.Individuals who have received cosmetic medical treatments such as peeling or laser therapy on the face or body within the past six months. 8.Individuals who themselves, or whose family members living in the same household, are employed in advertising agencies, market research or consulting firms, mass media, distribution, or in the manufacture of pharmaceuticals, cosmetics, toiletries, or hygiene products. 9.Individuals who are currently participating, or plan to participate during this study, in another interventional study (e.g., involving cosmetics or foods) targeting the facial skin. 10.Individuals who are deemed unsuitable for study participation by the principal investigator for any other reason.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change in skin surface roughness before and after 4 week use of skincare products | — |
Secondary
| Measure | Time frame |
|---|---|
| Skin color Stratum corneum moisture content TEWL value Skin surface roughness Wrinkle score Melanin index Hemoglobin index, etc. | — |
Countries
Japan
Contacts
Kao Corporation Skin Beauty Products Research Lab.