Healthy adults
Conditions
Interventions
To intake honey single time
To intake placebo single time
Sponsors
Shiba Palace Clinic
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) Japanese males and females aged 20 to 64 years old??at the time of informed consent 2) Healthy adults 3) Subjects who are concerned about coughing or throat discomfort 4) Subjects who regularly eat three meals a day 5) Subjects who Subjects who can perform informed consent 6) Subjects who can understand and comply with the management instructions during the study period
Exclusion criteria
Exclusion criteria: 1) Subjects who regularly consume honey 2) Subjects unable to maintain a regular daily routine 3) Pregnant, intending to become pregnant, or breastfeeding 4) Subjects participating in other clinical tests or studies during the test period 5) Subjects who are supposed not to be proper by the investigator 6) Subjects planning medication treatment for hay fever during the test period 7) Subjects unable to discontinue medications that may affect test results (e.g., cough suppressants, cold remedies, allergy suppressants) 7 days prior to the test 8) Subjects at risk of allergic reactions to test components (honey, chili pepper extract) 9) Subjects planning to change their diet during the test period 10) Subjects with cardiovascular or respiratory diseases, asthma, severe allergic diseases, liver dysfunction, kidney or heart disease, organ dysfunction, diabetes, or other serious illnesses 11) Subjects with a history of major gastrointestinal surgery (gastrectomy, gastrointestinal anastomosis, intestinal resection, etc.) 12) Subjects who consume excessive amounts of alcohol (equivalent to 20g of pure alcohol or more per day) 13) Smokers (or individuals living with smokers) 14) Subjects experiencing hay fever symptoms during the test period
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cough threshold in the capsaicin cough sensitivity test Japanese Newcastle Laryngeal Hypersensitivity Questionnaire(J-NLHQ) VAS questionnaire | — |
Secondary
| Measure | Time frame |
|---|---|
| subjects' diary doctor's findings according to the subjects' diary | — |
Countries
Japan
Contacts
Public ContactKo Masuda
SOUKEN Co., Ltd Management Division
Outcome results
None listed