Adult men and women
Conditions
Interventions
Participants will take one packet of proteoglycan-containing food (10 mg, Ichimaru Pharcos Co., Ltd.) between meals (between breakfast and lunch, lunch and dinner, or dinner and before bedtime) for 12
Sponsors
Kansai Electric Power Medical Research Institute
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: (1) Adult males and females (2) Subjects who can be evaluated at the start of the study and at weeks 4, 8, 12, and 20
Exclusion criteria
Exclusion criteria: (1) Subjects with skin disorders currently using topical medications (including moisturizers) on the measurement area. (2) Subjects currently using steroids. (3) Subjects with severe liver or renal dysfunction. (4) Subjects with heart failure (NYHA classification II or higher) that limits physical activity. (5) Subjects with severe infections, serious injuries, or arthritis. (6) Subjects with a salmon allergy. (7) Subjects currently or within the past three months have been taking functional foods, health foods, or supplements that claim to improve skin health. (8) Subjects with a history of cosmetic procedures or treatments on the measurement area within the past six months. (9) Subjects deemed inappropriate for this clinical study by the attending physician or principal investigator.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Changes in dermal collagen density over 20 weeks | — |
Secondary
| Measure | Time frame |
|---|---|
| Changes in stratum corneum moisture content over 20 weeks, Changes in dermal collagen thickness, Changes in the Mini-Nutrition Assessment (MNA-Short Form), Change in skin elasticity, Change in width of the area where elastin is denatured just below the epidermis | — |
Countries
Japan
Contacts
Public ContactShota Moyama
Kansai Electric Power Hospital Center for Metabolism and Clinical Nutrition
Outcome results
None listed