Skip to content

Prospective study of whether practicing thumb pronation improves pain and hand function in thumb CMC osteoarthritis

A prospective study of the effect of thumb pronation exercise on pain reduction and functional improvement in patients with thumb CMC osteoarthritis. - CMC-PRONE Study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000060287
Enrollment
25
Registered
2026-05-30
Start date
2026-04-30
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Thumb carpometacarpal arthritis

Interventions

In addition to regular rehabilitation, we provide instruction on thenar muscle training exercises, including opponens pollicis training.

Sponsors

Institute of Science Tokyo
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Thumh CMC osteoarthrits group: Those diagnosed with CM joint arthropathy of the thumb. Those diagnosed with the above disease by an orthopedic specialist based on medical history, physical findings, and imaging tests (plain X-rays). Those aged 20 years or older at the time of consent. Those who have given written consent to participate in this study.

Exclusion criteria

Exclusion criteria: Thumh CMC osteoarthrits group: Those with a history of trauma to the upper limbs or cervical spine. Those with rheumatoid arthritis or other collagen diseases. Those with a history of treatment for malignant tumors or other conditions affecting the upper limbs, shoulder girdle, or neck. Those with neurological paralysis due to cerebrovascular disease or other conditions. Those who have already received treatment at another hospital. Those deemed inappropriate by the principal investigator or co-investigator

Design outcomes

Primary

MeasureTime frame
Patient-rated questionnaire (Michigan Hand Outcome Questionnaire) scores

Secondary

MeasureTime frame
Pain intensity measured by the Numeric Rating Scale (NRS), Disabilities of the Arm, Shoulder and Hand (DASH) score, Patient Global Assessment, Treatment satisfaction, Joint range of motion (ROM), Grip strength, Pinch strength, Pain location, Nail Tip Angle of Thumb-Ring Finger Opposition, Thumb pronation angle, Surface electromyography amplitude ratio

Countries

Japan

Contacts

Public ContactTomoyuki Kuroiwa

Graduate School of Medical and Dental Sciences, Institute of Science Tokyo Department of Orthopaedic and Spinal Surgery

kuroiwa.orth@tmd.ac.jp0358035279

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026