Proprioceptive Prediction Error Neglect
Conditions
Interventions
Specific informational perturbation
Sham
Predictable informational perturbation
Mismatch informational perturbation
Specific informational perturbation under each subject'
s home
Sponsors
TIC-DO institute
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Health Status: Participants were healthy individuals with no history of psychiatric or neurological disorders and were not currently using psychotropic or neuroactive medications. Inclusion Criteria: Inclusion was restricted to individuals demonstrating latent proprioceptive deficits at baseline, defined as a Free Energy Proxy ($F$) > 0.8.
Exclusion criteria
Exclusion criteria: Psychiatric or neurological disorders and were currently prescribed psychotropic or neuroactive medications. Although the specific washout duration was not mandated in the initial IRB protocol, we enforced a strict 11-to-14 day washout period between sessions during the execution of all Studies. This duration was selected to ensure the complete resolution of any structural plasticity or synaptic consolidation effects, thereby isolating the transient informational effects of the intervention.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| We utilize Systemic Active Inference Metrics (SAIM), a novel framework of physiological indicators derived from EEG and heart rate variability (HRV) data. F (Free Energy Proxy): A metric indicating systemic uncertainty. NCI (Neural Complexity Index): A measure reflecting the complexity of neural activity. HEMO (Hemodynamic Coupling): An index representing neurovascular coupling. | — |
Countries
Japan
Contacts
Public ContactTakafumi Shiga
TIC-DO Research
Outcome results
None listed