Elucidation of Changes in Plasma Concentration and Protein Binding Ratio of Propofol during Co-administration with Remimazolam

Elucidation of Changes in Plasma Concentration and Protein Binding Ratio of Propofol during Co-administration with Remimazolam - Elucidation of Changes in Plasma Concentration and Protein Binding Ratio of Propofol during Co-administration with Remimazolam

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000060265

Enrollment

Registered

2026-01-06

Start date

2028-04-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

general anesthesia

Interventions

Co-administration of remimazola

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients undergoing elective non-cardiac surgery under general anesthesia

Exclusion criteria

Exclusion criteria: Patients with an allergy to propofol Patients with an allergy to remimazolam Patients who are on regular or as-needed benzodiazepine therapy

Design outcomes

Primary

Measure	Time frame
Propofol plasma concentration and protein binding ratio	—

Countries

Japan

Contacts

Public ContactHiroshi Ueda

Hamamatsu University School of Medicine Department of Medical Education, Faculty of Medicine

hueda-ham@umin.ac.jp0534352738

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026