Breast cancer patient
Conditions
Interventions
None listed
Sponsors
Yokohama City University Graduate School of Medicine
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: We will include only English full-articles. The other article including non-English article, short article, and conference abstract will be excluded. We will include parallel-group individual randomized controlled trials (RCTs) but not cluster RCTs, or cross-over RCTs. A trial with three or more arms will be accepted. Along with superiority trials, non-inferiority trials will be allowed. Any phase RCT may be included. Trials not reporting data about safety outcomes will be excluded. Key inclusion criteria are as follows. 1) Randomized controlled trials involving adult patients with breast cancer receiving anthracycline-based therapy. 2) Multi-arm trials in which at least one treatment arm includes anthracycline-based therapy. 3) Trials reporting outcomes related to the incidence of hypertension.
Exclusion criteria
Exclusion criteria: 1) Non-RCT. 2) The republished research literature is excluded unless the research includes new findings related to adverse events listed in inclusion criteria. 3) Studies with no or insufficient safety results at the time of the literature search. 4) Studies published in languages other than English. Two investigators independently screened all titles, abstracts, and full texts for eligibility. Final inclusion will be decided after resolving discrepancies between the two investigators.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of Hypertension Associated with Anthracycline Therapy | — |
Countries
Japan
Contacts
Public ContactShintaro Minegishi
Yokohama City University Graduate School of Medicine Department of Cardiology
Outcome results
None listed