Healthy adults
Conditions
Interventions
Tongue cleaning every morning for 3 months
Oil pulling every morning for 3 months
Mouthwash every morning for 3 months
No treatment
Sponsors
Kyoto University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Adults aged 18 years or older and younger than 65 years 2. Healthy individuals
Exclusion criteria
Exclusion criteria: 1. Individuals who have practiced tongue cleaning, oil pulling, or mouthwash use within the past month 2. Individuals who have taken, within the past month, medications (e.g., antibiotics, immunosuppressants, chemotherapy), probiotics, supplements, or functional foods that affect the gut microbiota 3. Women who are pregnant or breastfeeding 4. Individuals currently undergoing treatment for periodontitis 5. Individuals with sesame oil allergy 6. Individuals with a history of or currently undergoing treatment for malignant neoplasms of the digestive system 7. Any other individuals deemed inappropriate for participation in this study by the principal investigator
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Gut microbiota composition | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Gut microbiota diversity 2. Oral microbiota composition 3. Bowel consistency 4. Bowel movement 5. Oral health-related quality of life (OHRQoL) | — |
Countries
Japan
Contacts
Public ContactAkiko Tokinobu
Kyoto University Graduate School of Medicine
Outcome results
None listed