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Association between Acute Exercise-Induced Brain Region-Specific Endocannabinoid Expression and Anxiety-Like Behavior in Mice

Association between Acute Exercise-Induced Brain Region-Specific Endocannabinoid Expression and Anxiety-Like Behavior in Mice - Association between Acute Exercise-Induced Brain Region-Specific Endocannabinoid Expression and Anxiety-Like Behavior in Mice

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000060157
Enrollment
32
Registered
2025-12-22
Start date
2025-07-15
Completion date
Unknown
Last updated
2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy male mice

Interventions

non-stress+rest, the stress condition consisted of restraint in a 50-mL conical tube for 2 hours, while the exercise condition involved treadmill running at 10 m/min. non-stress+exercise, the stress c

Sponsors

Yamanashi Gakuin University
Lead Sponsor

Eligibility

Sex/Gender
Male

Inclusion criteria

Inclusion criteria: Healthy male C57BL/6J mice, aged 8 weeks, experimentally naive, and acclimatized to laboratory conditions.

Exclusion criteria

Exclusion criteria: Mice were excluded from the analysis if they showed visible signs of injury or refused to run on the treadmill despite encouragement.

Design outcomes

Primary

MeasureTime frame
Brain endocannabinoid concentrations (post-intervention)—

Secondary

MeasureTime frame
Plasma endocannabinoid concentrations (post-intervention) Anxiety-like behavior (Open Field Test, Elevated Plus Maze; post-intervention)—

Countries

Japan

Contacts

Public ContactTETSUYA YABE

Yamanashi Gakuin University Faculty of Sport Science

yabe.tetsuya@c2c.ac.jp055-224-1377

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Sep 19, 2026