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Construction of a Large-Scale Database for Machine Learning in Brain Imaging

Construction of a Large-Scale Database for Machine Learning in Brain Imaging - Construction of a Large-Scale Database for Machine Learning in Brain Imaging

Status
Recruiting
Phases
Unknown
Study type
Unknown
Source
JPRN
Registry ID
JPRN-UMIN000060069
Enrollment
Unknown
Registered
2025-12-26
Start date
2022-04-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Mental Disorders and Healthy Controls

Interventions

None listed

Sponsors

Keio University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Inclusion Criteria 1. MRI brain images are available. 2. Information regarding age or sex is available. Include cases that meet the above inclusion criteria. Include cases with available MRI brain images and age/sex information necessary for creating a baseline model based on age and sex.

Exclusion criteria

Exclusion criteria: Participation in the study will be discontinued for a subject if any of the following criteria apply: 1) The subject requests to withdraw from the study or withdraws consent. 2) Ineligibility is determined after enrollment. 3) A major violation of the study protocol is identified. 4) Other circumstances deemed necessary by the Principal Investigator or Co-Investigator [Withdrawal Procedure] (a) Patients withdrawn from the study will not undergo further evaluations for the study. (b) There are no plans to add additional cases due to early withdrawal of research subjects.

Design outcomes

Primary

MeasureTime frame
This is an analysis plan for dataset creation and utilization of the created database. <Inclusion Criteria> 1. Brain images acquired via MRI are available. 2. Information regarding age or gender is available. Cases meeting the above inclusion criteria will be included. <Analysis> Common preprocessing will be applied to the acquired brain image data. These preprocessed images will serve as the final input images for machine learning, enabling the creation of high-accuracy models based on age and gender. For high-accuracy model creation, deep learning will be employed in addition to conventional machine learning. Using the age and gender prediction models created from the large dataset above, the following models will be developed using a dataset rich in clinical information available at the Department of Psychiatry, Keio University School of Medicine: a cognitive function prediction model, a mental disorder prediction model, a mental disorder treatment effect prediction model, and a brain substance prediction model.

Countries

Japan

Contacts

Public ContactJinichi Hirano

Keio University School of Medicine

hjinichi@keio.jp03-5363-3971

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026