Listening Difficulties / Auditory Processing Disorder
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1 participants who have provided written informed consent to participate in the study 2 participants who own a device capable of accessing the audio materials such as a smartphone tablet or personal computer or who have access to a device capable of playing CDs young adults with normal hearing 1 age between 20 and 40 years at the time of consent 2 normal hearing as confirmed by pure tone audiometry four frequency pure tone average pta method B 30 dB or less 3 no subjective symptoms of listening difficulties older adults with normal hearing 1 age 65 years or older at the time of consent 2 normal hearing as confirmed by pure tone audiometry four frequency pure tone average pta method B 30 dB or less 3 no subjective symptoms of listening difficulties patients with lid apd 1 age 20 years or older at the time of consent 2 diagnosed with listening difficulties auditory processing disorder lid apd in our department between january 2020 and december 2024 in accordance with the proposed diagnostic criteria described in guidelines for the diagnosis and support of lid apd first edition 2024 amed research outcomes proposed diagnostic criteria all of the following must be met 1 pure tone audiometry bilateral hearing thresholds less than 25 dB four frequency pta method B 2 speech intelligibility in quiet 85 percent or more 3 presence of subjective listening difficulties defined as i a score of 109 or less on the questionnaire on listening difficulties developed by Kobuchi et al or ii a score of 6 or more on the checklist for detection of listening difficulties developed by Ogawa et al
Exclusion criteria
Exclusion criteria: 1 individuals who have contraindications to MRI examination or magnetoencephalography including cochlear implants MRI incompatible cardiac pacemakers or claustrophobia 2 individuals who are pregnant or planning to become pregnant at the time of consent 3 individuals with abnormal findings of the external auditory canal or tympanic membrane 4 individuals who are not suitable for MRI imaging or meg measurement including those who have metal in the body such as cardiac pacemakers prosthetic heart valves cochlear or middle ear implants non titanium cerebral aneurysm clips artificial joints orthopedic fixation bolts magnetic dentures implants orthodontic devices tattoos permanent makeup intrauterine devices or metallic foreign bodies in the eyes, and individuals with claustrophobia
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Brain regions showing activation or suppression on magnetoencephalography during sentence listening under noisy conditions will be compared among three groups, young normal hearing adults aged 20 to 40 years, older normal hearing adults aged 65 years or older, and patients with listening difficulties or auditory processing disorder diagnosed in our department. In addition, after implementing our original auditory rehabilitation program, MEG will be performed again under the same conditions to evaluate whether differences in activated or suppressed regions are observed before and after rehabilitation. | — |
Secondary
| Measure | Time frame |
|---|---|
| Using the Japanese Hearing in Noise Test (J-HINT), we will evaluate whether speech perception in noise is reduced in the older adult group and the LiD/APD patient group compared with the young adult group, and whether speech perception in noise improves before and after auditory training. | — |
Countries
Japan
Contacts
Osaka Metropolitan University Otolaryngology