A Study on the Effectiveness of a Self-Care Support Application for Menopausal Symptoms

Effectiveness of a Self-Care Support Mobile Application for Menopausal Symptoms in Midlife Women: A Randomized Controlled Trial - Self-Care Support Smartphone App for Menopausal Symptoms: RCT

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000060039

Enrollment

400

Registered

2026-01-05

Start date

2026-01-05

Completion date

Unknown

Last updated

2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Menopausal symptoms

Interventions

The intervention group will use the JoyHer Pro app for 12 weeks. The control group will use a limited-function app for 12 weeks.

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: Japanese Irregular menstrual cycles or absence of menstruation within the past year Presence of any menopausal symptoms (Menopause Rating Scale [MRS] score of 5 or higher) Ownership of an iPhone (iOS 16 or later) with daily availability of mobile data communication Ability to communicate and use the app in Japanese without difficulty

Exclusion criteria

Exclusion criteria: Presence of the following comorbidities: coronary artery disease (such as angina or myocardial infarction), pheochromocytoma, psychiatric disorders (such as depression or schizophrenia), malignant tumors under treatment, uncontrolled thyroid dysfunction (with treatment changes within the last 3 months), or uncontrolled hypertension (with treatment changes within the last 3 months) Started new medications (e.g., hormone replacement therapy or antidepressants) within the past 30 days. Pregnant or breastfeeding. Has previously used any of the following applications: JoyHer, JoyHer for Business, or JoyHer Pro.

Design outcomes

Primary

Measure	Time frame
Comparison of group differences in the total score of the Menopause Rating Scale (MRS) measured at baseline, 4, 8, and 12 weeks after intervention using Mixed Model for Repeated Measures (MMRM).	—

Secondary

Measure	Time frame
Subscales of the Menopause Rating Scale (MRS) Simplified Menopausal Index (SMI) Numerical Rating Scale (NRS) for symptoms such as stiff shoulders, coldness, dizziness, headache, fatigue, and weather sensitivity Kessler 6 Psychological Distress Scale (K6) Gastrointestinal Symptom Rating Scale (GSRS) SF36 Work Productivity and Activity Impairment Questionnaire: General Health (WPAI-GH) Self Compassion Scale Short Form Knowledge, attitudes, and coping ability related to menopause Use of medical and health services and reasons for consultations Global improvement assessment Blinding status Allocation concealment awareness Net Promoter Score (NPS)	—

Measure

Time frame

Subscales of the Menopause Rating Scale (MRS) Simplified Menopausal Index (SMI) Numerical Rating Scale (NRS) for symptoms such as stiff shoulders, coldness, dizziness, headache, fatigue, and weather sensitivity Kessler 6 Psychological Distress Scale (K6) Gastrointestinal Symptom Rating Scale (GSRS) SF36 Work Productivity and Activity Impairment Questionnaire: General Health (WPAI-GH) Self Compassion Scale Short Form Knowledge, attitudes, and coping ability related to menopause Use of medical and health services and reasons for consultations Global improvement assessment Blinding status Allocation concealment awareness Net Promoter Score (NPS)

—

Countries

Japan

Contacts

Public ContactTakuma Ohsuga

Graduate School of Medicine, Kyoto University Department of Obstetrics and Gynecology

whc6_adm@kuhp.kyoto-u.ac.jp075-751-3284

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Sep 19, 2026