Hip fracture or vertebral fracture
Conditions
Interventions
A vitamin D-fortified milk beverage containing 9.0 micrograms of vitamin D per bottle will be provided once daily at breakfast from admission to discharge.
A milk beverage without vitamin D will be
Sponsors
Yoshida Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Patients admitted with proximal femoral fracture or vertebral fracture 2. Patients or their representatives who provide written informed consent
Exclusion criteria
Exclusion criteria: 1. Patients with contraindications to dairy products (such as allergy or intolerance) 2. Patients with severe swallowing disorders that make oral intake of the milk beverages difficult 3. Patients judged by the attending physician to be medically unsuitable for participation
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change in serum 25(OH)D levels from admission to discharge. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Improvement rate of vitamin D deficiency (proportion of patients with serum 25(OH)D >= 20 ng/mL at discharge) 2. Serum 25(OH)D level at discharge 3. Changes in Functional Independence Measure (FIM) scores 4. Change in Skeletal Muscle Mass Index (SMI) 5. Incidence of adverse events, defined as decreased renal function (eGFR < 60 mL/min/1.73m2) or hypercalcemia (serum calcium >= 10.5 mg/dL) | — |
Countries
Japan
Contacts
Public ContactAraki Saito
Yoshida Hospital Department of Nutrition
Outcome results
None listed