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Effects of geranium essential oil on autonomic nervous system in hospital staff: a randomized crossover study.

Geranium essential oil and Autonomic Nervous System Study: randomized crossover trial in hospital staff - G-ANS

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000060018
Enrollment
60
Registered
2025-12-15
Start date
2025-12-15
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Stress-related symptoms

Interventions

A 10 minute oil treatment was applied to one arm using 0.1% diluted geranium essential oil. 10 minute oil treatment for one arm using only base oil (macadamia nut oil).

Sponsors

Dokkyo Medical University Nikko Medical Center Department of Pharmacy Ryuichiro Masubuchi
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: The subject is a healthy individual employed at Dokkyo Medical University Nikko Medical Center, with no history of significant physical or mental illness. The individual in question has been the recipient of a sufficient explanation and has provided written consent.

Exclusion criteria

Exclusion criteria: The following criteria were considered in the exclusion of subjects from the study: allergies to geranium essential oil or macadamia nut oil; pregnancy or breastfeeding; history of diagnosis with heart disease, respiratory disease, autonomic nervous system disorders, or mental illness; hypersensitivity to fragrances; extreme sleep deprivation or immediately after night shifts; constraints that would interfere with interventions or measurements; recent initiation of medications affecting the autonomic nervous system; or individuals deemed unsuitable by the principal investigator.

Design outcomes

Primary

MeasureTime frame
The following investigation will examine the alterations in heart rate variability (HRV) and the LF/HF ratio in the immediate period preceding and following the intervention.

Countries

Japan

Contacts

Public ContactRyuichiro Masubuchi

Dokkyo Medical University Nikko Medical Center Department of Pharmacy

r-masubuchi@dokkyomed.ac.jp0288-23-7000

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026