traumatic brain injury
Conditions
Interventions
None listed
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Patients aged 16 years or older with traumatic brain injury will be included. A comprehensive literature search will be conducted to capture a wide range of relevant studies. The characteristics of the retrieved studies will then be examined to ensure clinical and methodological consistency across patient populations, after which eligible studies will be selected for inclusion in the meta-analysis. Studies that do not meet the eligibility criteria but are considered relevant will be summarized narratively.
Exclusion criteria
Exclusion criteria: 1. Studies not involving human subjects 2. Pediatric cases (patients younger than 16 years) 3. Subgroup analyses in which no traumatic brain injury cases are included 4. Single-arm studies, case reports, conference abstracts, or protocol-only publications 5. Articles not written in English
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| mortality | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Total transfusion volume (red blood cells, fresh frozen plasma, and platelet concentrates) 2. Complications: thrombosis (pulmonary embolism, deep vein thrombosis), acute kidney injury, pulmonary edema, acute respiratory distress syndrome, and infection | — |
Countries
Japan
Contacts
National Defense Medical College Traumatology and Critical Care Medicine