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Safety and efficacy of home-based neuromuscular electrical stimulation device in patients with Charcot-Marie-Tooth disease: a randomized controlled crossover trial

Safety and efficacy of home-based neuromuscular electrical stimulation device in patients with Charcot-Marie-Tooth disease: a randomized controlled crossover trial - Neuromuscular electrical stimulation (NMES) training in CMT

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000059903
Enrollment
40
Registered
2025-12-01
Start date
2022-11-17
Completion date
Unknown
Last updated
2025-12-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Charcot-Marie-Tooth disease

Interventions

Neuromuscular electrical stimulation training for lower leg muscles Control

Sponsors

Kyoto prefectural university of medicine
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria:

Exclusion criteria

Exclusion criteria: Exclusion criteria were as follows: no muscle contraction of the lower leg muscles observed with the NMES device; History of lower extremity trauma; already undergoing NMES training at the time of informed consent; comorbid peripheral neuropathy other than CMT or muscle disease; use of medications that may affect nerves or muscles; or excessive alcohol consumption; presence of implantable medical electrical devices such as pacemakers; presence of metallic implants such as metal plates in the lower extremities; pregnant or lactating women; any other safety-related reasons deemed inappropriate for study participation by the principal investigator or co-investigators.

Design outcomes

Primary

MeasureTime frame
Lower leg muscle strength

Countries

Japan

Contacts

Public ContactYu-ichi Noto

Kyoto prefectural university of medicine hospital Department of Neurology

y-noto@koto.kpu-m.ac.jp075-251-5794

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Feb 4, 2026