Healthy Japanese
Conditions
Interventions
Duration: Eight weeks Test product: Test food
Sponsors
ORTHOMEDICO Inc.
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Japanese 2. Men or women 3. Adults 4. Healthy individuals 5. Individuals who have recently experienced skin problems
Exclusion criteria
Exclusion criteria: 1. Individuals currently undergoing treatment or with a medical history of malignant tumor, heart failure, or myocardial infarction 2. Individuals with a pacemaker or implantable cardioverter defibrillator 3. Individuals currently undergoing treatment for chronic diseases such as cardiac arrhythmia, liver disorder, chronic kidney disease, cerebrovascular disorder, rheumatic disease, diabetes mellitus, dyslipidemia, hypertension, or other chronic diseases 4. Individuals taking Foods for Specified Health Uses or Foods with Functional Claims 5. Individuals taking medicines (including herbal medicines) or supplements 6. Individuals with a history of atopic dermatitis 7. Individuals using daily skincare products other than toners, lotions, or sunscreen, such as creams, serums, all-in-one products, and masks 8. Individuals regularly receiving skincare treatments (e.g., aesthetic procedures) or using beauty devices (e.g., facial devices) 9. Individuals with a history of cosmetic surgery 10. Individuals who have undergone any procedures in the past 3 months that may affect the evaluation site, such as hormone replacement therapy, cosmetic procedures, or treatments for diseases requiring hospitalization 11. Individuals at risk of seasonal allergy symptoms, such as hay fever, during the study 12. Individuals whose lifestyle patterns may vary during the study (e.g., night shifts, business trips, or travel) 13. Individuals unable to refrain from deliberate exposure to sunlight, such as sunbathing, during the study 14. Individuals with allergies to medicines or foods related to the test product, particularly cacao allergy 15. Individuals who are pregnant, lactating, or planning to become pregnant during the study period 16. Individuals who participated in another clinical study within 28 days before consent or plan to participate in another study during the study 17. Individuals considered ineligible for the study by the principal investigator
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Measured value of transepidermal water loss (TEWL) at 8 weeks after the intervention (8w) | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Measured value of TEWL at 4 weeks after the intervention (4w) 2. Measured values of skin surface moisture at 4w and 8w 3. Measured values of skin viscoelasticity (R0-R9) at 4w and 8w | — |
Countries
Japan
Contacts
Public ContactNaoko Suzuki
ORTHOMEDICO Inc. R&D Department
Outcome results
None listed