Diabetic peripheral neuropathy as an independent predictor of renal function decline in type 2 diabetes: a propensity score-matched retrospective cohort study using DPN-Check

Diabetic peripheral neuropathy as an independent predictor of renal function decline in type 2 diabetes: a propensity score-matched retrospective cohort study using DPN-Check - Diabetic peripheral neuropathy as an independent predictor of renal function decline in type 2 diabetes: a propensity score-matched retrospective cohort study using DPN-Check

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000059867

Enrollment

400

Registered

2025-11-24

Start date

2025-08-06

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Type 2 diabetes

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Japanese patients with type 2 diabetes who did not have foot ulcers and underwent nerve conduction assessment using DPN-Check between June 2015 and April 2017.

Exclusion criteria

Exclusion criteria: Patients who were transferred to another medical institution or discontinued treatment within 5 years of the start of observation, and those who died due to unknown causes or unrelated to kidney disease

Design outcomes

Primary

Measure	Time frame
Incidence of renal events, defined as a >30% decline in eGFR from baseline, initiation of renal replacement therapy, or death due to renal or cardiovascular disease.	—

Countries

Japan

Contacts

Public ContactHiroyuki Ito

Edogawa Hospital Department of Diabetes, Metabolism and Kidney Disease

ito@edogawa.or.jp+81-3-3673-1221

Outcome results