Effect of 6 Weeks of Balance Training With or Without Blood Flow Restriction on Pain, Muscle Strength, and Functional Performance in Athletes With Chronic Ankle Instability

Effects of Six Weeks of Balance Training With or Without Proximal-Shank Blood Flow Restriction on Pain, Ankle Muscle Strength, Perceived Instability, Dynamic Balance, Proprioception, and Functional Performance in Athletes With Chronic Ankle Instability: A Randomized Controlled Trial - Effects of Six Weeks of Balance Training With or Without Proximal-Shank Blood Flow Restriction on Pain, Ankle Muscle Strength, Perceived Instability, Dynamic Balance, Proprioception, and Functional Performance in Athletes With Chronic Ankle Instability: A Randomized Controlled Trial (BFR-BT-CAI)

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000059860

Enrollment

Registered

2025-11-30

Start date

2025-11-03

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Functional Ankle Instability

Interventions

6 weeks, 3 sessions/week, 30-45 min per session. Identical progressive unilateral balance exercises (single-leg stance, squats, hops, tuck jumps, ball tasks, unstable surfaces, eyes closed progression

Eligibility

Sex/Gender

Male

Inclusion criteria

Inclusion criteria: Male recreational or competitive athlete At least two episodes of giving way at the ankle in the past 6 months Unilateral chronic functional ankle instability

Exclusion criteria

Exclusion criteria: Key Exclusion Criteria Bilateral chronic ankle instability Mechanical ankle instability (positive anterior drawer or talar tilt test >1+ on clinical examination) Acute ankle sprain or lower-extremity injury within the previous 3 months History of fracture or surgery in the lower extremity Neurological, vestibular, or severe visual impairment that affects balance Diagnosed deep vein thrombosis, peripheral vascular disease, or any absolute contraindication to blood flow restriction Hypertension (resting blood pressure >140/90 mmHg) Current participation in a formal ankle rehabilitation or strength-training program Inability or unwillingness to adhere to the 6-week supervised training protocol (3 sessions/week) Any medical condition that, in the opinion of the investigator, would make BFR or intensive balance training unsafe Female sex (study limited to male participants only)

Design outcomes

Primary

Measure	Time frame
To determine whether adding proximal-shabk blood flow restriction (BFR) to a 6-week progressive balance training program results in greater reductions in pain and perceived ankle instability, as well as larger improvements in dynamic postural control, compared to the same balance training program performed without BFR in athletes with chronic ankle instability (CAI).	—

Countries

Asia(except Japan)

Contacts

Public ContactAynollah Naderi

Shahrood University of Technology Sport science

ay.naderi@shahodut.ac.ir02332392204

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026