Effects of Concurrent Transcutaneous Auricular Vagus Nerve Stimulation (taVNS) and Continuous Deep Breathing/Aerobic Exercise on Pain Inhibition

Effects of Concurrent Transcutaneous Auricular Vagus Nerve Stimulation (taVNS) and Continuous Deep Breathing/Aerobic Exercise on Pain Inhibition - Effects of Concurrent Transcutaneous Auricular Vagus Nerve Stimulation (taVNS) and Continuous Deep Breathing/Aerobic Exercise on Pain Inhibition

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000059838

Enrollment

Registered

2025-11-22

Start date

2025-12-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic pain

Interventions

Participants will perform deep breathing for 10 minutes per day for 14 days while receiving transcutaneous auricular vagus nerve stimulation on the cymba conchae (continuous deep breathing and active

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Healthy undergraduate or graduate students

Exclusion criteria

Exclusion criteria: Individuals with a personal or family history of epilepsy, anxiety disorders, or cardiovascular disease, Pregnant individuals, Individuals experiencing pain, Individuals who exercise three or more times per week

Design outcomes

Primary

Measure	Time frame
pressure pain threshold at rest	—

Secondary

Measure	Time frame
heart rate variability, salivary amylase concentration, state-trait anxiety inventory, respiratory rate at rest, accuracy and response time in the Stroop test	—

Countries

Japan

Contacts

Public ContactKatsuaki Yamanami Yamanami

Graduate School Niigata University of Health and Welfare Graduate School of Medical and Welfare Studies

hpm24005@nuhw.ac.jp090-4135-3635

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026