Diagnostic performance of endoscopic features for sessile serrated lesions: comparison between the Japanese Classification of Colorectal, Appendiceal, and Anal Carcinoma (3rd English Edition) and the WHO 5th edition histopathological criteria

Diagnostic performance of endoscopic features for sessile serrated lesions: comparison between the Japanese Classification of Colorectal, Appendiceal, and Anal Carcinoma (3rd English Edition) and the WHO 5th edition histopathological criteria - Endoscopic diagnosis of SSLs under Japanese and WHO criteria

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000059820

Enrollment

140

Registered

2025-11-20

Start date

2025-11-25

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

sessile serrated lesion

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Lesions that were endoscopically resected and histopathologically diagnosed as serrated lesions, including hyperplastic polyp (HP), sessile serrated adenoma/polyp (SSA/P), sessile serrated lesion (SSL), or microvesicular hyperplastic polyp (MVHP). Only specimens that were adequately preserved and suitable for histopathological evaluation were included.

Exclusion criteria

Exclusion criteria: Traditional serrated adenoma (TSA) Poorly preserved or inadequate specimens Serrated polyposis syndrome (SPS)

Design outcomes

Primary

Measure	Time frame
Diagnostic performance of SSL detection using endoscopic scores (AUC: Area Under the ROC Curve) Comparison of AUC values between the Japanese Classification and the WHO 5th edition criteria	—

Countries

Japan

Contacts

Public ContactKOICHI HAMADA

Southern-Tohoku General Hospital Department of Gastroenterology

ag14072@yahoo.co.jp0249345322

Outcome results