Research on Facial Morphological Changes and Psychophysiological Effects Induced by Acupoint Stimulation

A Study on Facial Morphological Changes and Psychophysiological Responses to Acupoint Stimulation - On the Effects of Acupoint Stimulation on the Facial Region and the Mind Body System

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000059811

Enrollment

Registered

2025-11-18

Start date

2025-11-21

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

healthy adults

Interventions

Acupressure will be applied to the facial acupoints Quanliao (SI18), Xiaguan (ST7), and Taiyang.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) Healthy adults aged 20 to 65 years; 2) Individuals who have provided informed consent to participate in the study.

Exclusion criteria

Exclusion criteria: Individuals who do not meet the inclusion criteria

Design outcomes

Primary

Measure	Time frame
1.Facial morphological changes assessed by 3D image analysis Objective measurements of facial shape differences before and after the intervention using the Vectra H2 system (e.g., changes in cheek volume, facial contour, and degree of lift). 2.Changes in salivary amylase levels Evaluation of stress responses before and after the intervention, using salivary amylase as an index of autonomic nervous system activity.	—

Measure

Time frame

1.Facial morphological changes assessed by 3D image analysis Objective measurements of facial shape differences before and after the intervention using the Vectra H2 system (e.g., changes in cheek volume, facial contour, and degree of lift). 2.Changes in salivary amylase levels Evaluation of stress responses before and after the intervention, using salivary amylase as an index of autonomic nervous system activity.

—

Secondary

Measure	Time frame
1.Changes in subjective relaxation Subjective evaluation using a questionnaire based on the shortened version of the Relaxation Rating Scale. 2.Subjective sensations after the intervention Including mood, sense of lightness, overall comfort, and satisfaction. 3.Assessment of discomfort and safety during the intervention Evaluation of any discomfort experienced and the presence or absence of adverse events.	—

Measure

Time frame

1.Changes in subjective relaxation Subjective evaluation using a questionnaire based on the shortened version of the Relaxation Rating Scale. 2.Subjective sensations after the intervention Including mood, sense of lightness, overall comfort, and satisfaction. 3.Assessment of discomfort and safety during the intervention Evaluation of any discomfort experienced and the presence or absence of adverse events.

—

Countries

Japan

Contacts

Public Contactmichiyo takano

Niigata University of Health and Welfare Department of Acupuncture, Moxibustion and Health

michiyo-takano@nuhw.ac.jp0252501918

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026