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Acute Effects of Normobaric Hypoxia on Skeletal Muscle Microvascular Function

Acute Effects of Normobaric Hypoxia on Skeletal Muscle Microvascular Function - Acute Effects of Normobaric Hypoxia on Skeletal Muscle Microvascular Function

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000059793
Enrollment
16
Registered
2025-11-17
Start date
2025-11-11
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sleep Apnea Syndrome

Interventions

Attach a mask to a balloon filled with air containing 15% oxygen concentration and inhale the air from the balloon for 10 minutes. Do not connect to the balloon
inhale room air for 10 minutes.

Sponsors

Niigata University of Health and Welfare
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Participants must be between 18 and 30 years of age at the time consent is obtained. Participants must have received a thorough explanation regarding this research and provided written consent of their own free will after demonstrating sufficient understanding.

Exclusion criteria

Exclusion criteria: Individuals aged 31 years or older Individuals with a history of cardiovascular disease or currently receiving medication for such conditions Individuals currently taking medication or supplements Individuals with a regular exercise routine (performing at least 150 minutes of moderate-intensity aerobic exercise or 75 minutes of vigorous-intensity aerobic exercise per week) Individuals with a history of smoking Other individuals deemed unsuitable for the study by the principal investigator

Design outcomes

Primary

MeasureTime frame
Microvascular Function of the Gastrocnemius Muscle Before and After Exposure to 15% Oxygen Concentration

Secondary

MeasureTime frame
Heart rate, stroke volume, cardiac output, mean arterial pressure, and SpO2 before and after a 10-minute exposure intervention at 15% inspired oxygen concentration, and during the intervention

Countries

Japan

Contacts

Public ContactYoshino Takuro

Niigata University of Health and Welfare Graduate School of Medical and Welfare Sciences, Department of Health Sciences, Physical Therapy

hpm25022@nuhw.ac.jp090-6795-4327

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026