Healthy
Conditions
Interventions
Cognitive behavioral Training of Interoception: The interoception training task (approx. 30 minutes) using a PC program will be administered once daily for 5 consecutive days.
taVNS stimulation: 30
Sponsors
National Center for Neurology and Psychiatry, National Institute of Mental Health
Tamagawa University Brain Science Institute Tokyo Kasei Gakuin University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) Individuals aged 18 to 59 years at the time of informed consent. 2) Healthy adults with no regular hospital visits or medication use.
Exclusion criteria
Exclusion criteria: Behavioral Experiments Individuals with a cochlear implant, cardiac pacemaker, or implanted Vagus Nerve Stimulator (VNS). Individuals with an injury to the auricular area (ear). Individuals who have undergone a cerebrospinal fluid (CSF) shunt procedure. Individuals with a diagnosis of glaucoma. Smokers. Individuals with frequent cardiac arrhythmias. Individuals whose resting heart rate is consistently below 60 beats per minute (bpm). MRI Experiments Individuals with a cochlear implant, cardiac pacemaker, or implanted VNS. Individuals for whom MRI scanning poses a certain risk (e.g., tattoos, permanent make-up/cosmetic tattoos, claustrophobia, or other metallic implants/devices). Individuals with an injury to the auricular area (ear). Individuals who have undergone a cerebrospinal fluid (CSF) shunt procedure. Individuals with a diagnosis of glaucoma. Smokers. Individuals with frequent cardiac arrhythmias. Individuals whose resting heart rate is consistently below 60 beats per minute (bpm).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The following assessments will be performed before and after the 5-day intervention: Altruistic behavior measures Change in brain MRI images | — |
Secondary
| Measure | Time frame |
|---|---|
| State Trait Anxiety Inventory Japanese version and Social Anxiety Disorder Scale Japanese version The Center for Epidemiologic Studies Depression Scale Japanese version Rate of change in Heart Rate Heartbeat Counting Task Metacognition Task Executive Function Measurement Social Value Orientation Multidimensional Assessment of Interoceptive Awareness Japanese version Japanese version of the Patient Health Questionnaire 15 Wellbeing scales Positive Affect Negative Affect Scale Japanese version Psychological Wellbeing Japanese version Cantrils ladder Satisfaction with Life Scale | — |
Countries
Japan
Contacts
Public ContactRuri Katsunuma
National Center for Neurology and Psychiatry, National Institute of Mental Health Department of Behavioral Medicine
Outcome results
None listed