Effect of treatment with compression gloves/stockings and ice packs to prevent paclitaxel-induced peripheral neuropathy - Phase 2 study

Effect of treatment with compression gloves/stockings and ice packs to prevent paclitaxel-induced peripheral neuropathy - Effect of treatment with compression gloves/stockings and ice packs to prevent paclitaxel-induced peripheral neuropathy

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000059735

Enrollment

Registered

2025-11-11

Start date

2022-11-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Breast cancer

Interventions

wear two surgical gloves and stockings

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: 1) Considered eligible to neoadjuvant or adjuvant weekly paclitaxel therapy (80mg/m2, 12 doses) 2)ECOG performance status 0-1 3)Signed written informed consent

Exclusion criteria

Exclusion criteria: 1)Poorly controlled complication (infection, diabetes mellitus, and others) 2)Severe pleural effusion and ascites 3)Pregnant or possibly pregnant 4)have with Grade 2 or higher peripheral sensory neuropathy (CTCAE ver4.0) 5)received previous taxane chemotherapy

Design outcomes

Primary

Measure	Time frame
Incidence of Grade 2 or higher peripheral sensory neuropathy in the hands	—

Countries

Japan

Contacts

Public ContactYuri Tamura

Osaka City General Hospital Department of Breast Surgical Oncology

wbykk742@gmail.com06-6929-1221

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026