idiopathic pulmonary fibrosis
Conditions
Interventions
None listed
Sponsors
Yokohama City University Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Population: patients with idiopathic pulmonary fibrosis (IPF). Diagnostic certainty: possible, probable, or definite IPF will be treated collectively as IPF if permitted by the original study design. Comorbidities: no restriction; comorbid conditions are not grounds for exclusion. IPAF: included if diagnosed as IPF and without a confirmed diagnosis of any collagen vascular disease.
Exclusion criteria
Exclusion criteria: Studies that enroll patients with active or ongoing acute exacerbation at baseline. Studies primarily recruiting non-IPF interstitial lung diseases (e.g., confirmed connective tissue disease-associated ILD). Non-human, pediatric-only, or non-clinical studies that do not match the target patient population.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The weighted Pearson's correlation coefficient (r) between the hazard ratios for surrogate endpoints - exacerbation-based (HR_ex) and composite survival endpoints (HR_comp) - and the hazard ratio for overall survival (HR_OS). | — |
Countries
Japan
Contacts
Public ContactNobuyuki Horita
Yokohama City University Hospital Department of Respiratory Medicine
Outcome results
None listed