Prospective Observational Study of Hypofractionated Postprostatectomy Salvage Radiation Therapy (HYPOST)

Prospective Observational Study of Hypofractionated Postprostatectomy Salvage Radiation Therapy (HYPOST) - HYPOST study

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000059723

Enrollment

Registered

2025-11-10

Start date

2025-11-10

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative biochemical recurrence of prostate cancer

Interventions

None listed

Eligibility

Sex/Gender

Male

Inclusion criteria

Inclusion criteria: (i) HYPOST is planned to be performed in our hospital for postoperative biochemical recurrence of prostate cancer. (2) The patient has given consent for HYPOST. (iii) The patient is able to lie in a supine position at rest.

Exclusion criteria

Exclusion criteria: (i) Previous history of radiotherapy to the pelvic region. (ii) The patient has complications that contraindicate radiotherapy, such as active collagen disease, ulcerative colitis or Crohn's disease. (iii) The patient had pN1 at the time of the prostatectomy. (iv) The patient has a severe mental disorder or has difficulty in speaking or interviewing in Japanese.

Design outcomes

Primary

Measure	Time frame
Acute adverse event rate	—

Secondary

Measure	Time frame
EPIC, EQ-5D-5L, 2-year late adverse event rate, 2-year biochemical relapse-free survival, 2-year overall survival, and 2-year prostate cancer-specific survival	—

Countries

Japan

Contacts

Public ContactKiyonao Nakamura

Kyoto city hospital Department of radiation oncology

kiyonaka@kuhp.kyoto-u.ac.jp075-311-5311

Outcome results