Typical atrioventricular nodal reentrant tachycardia
Conditions
Interventions
Cryoablation will be performed for typical atrioventricular nodal reentrant tachycardia guided by local activation time velocity vector analysis using the CARTO3 system.
Sponsors
Gifu Prefectural General Medical Center
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Participants who meet all of the following conditions will be enrolled: 1.Age 18 years or older. 2.Patients diagnosed with typical atrioventricular nodal reentrant tachycardia (slow-fast type) based on clinical findings and electrophysiological study. 3.Patients scheduled to undergo cryoablation with target localization guided by Local Activation Time Velocity Vector (LVV) analysis using the CARTO3 three-dimensional mapping system. 4.Patients who have received a full explanation of the study purpose and methods and have provided written informed consent. 5.Patients expected to be available for outpatient follow-up at 3 months after the procedure.
Exclusion criteria
Exclusion criteria: Participants meeting any of the following conditions will be excluded: 1.History of previous ablation for atrioventricular nodal reentrant tachycardia (AVNRT). 2.Patients whose primary arrhythmia mechanism is a manifest accessory pathway (for example, overt atrioventricular reentrant tachycardia). 3.Cases in which Kochs triangle cannot be adequately identified, making proper LVV analysis or target localization unfeasible. 4.Patients with severe atrioventricular conduction disturbance or marked bradycardia, in whom the investigator judges that study participation would compromise safety. 5.Pregnant women or those with a high likelihood of pregnancy. 6.Patients with serious comorbidities (for example, active infection or uncontrolled heart failure) that make study participation inappropriate in the judgment of the investigator. 7.Patients who are unable or unwilling to provide written informed consent, or who subsequently withdraw consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The proportion of cases in which non-inducibility of tachycardia is achieved by cryoablation performed only within the target area identified by Local Activation Time Velocity Vectors (LVV hot spot) (First-site success rate). In cases of failure, the reason (safety concern, insufficient effect, or technical difficulty) will be recorded. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1.Acute procedural success rate. 2.Number of cryoablation applications (each application defined as one 240-second freeze cycle). 3.Total cryoablation time. 4.Total procedure time. 5.Fluoroscopy time and radiation dose (dose area product: DAP). 6.Change in PQ interval (pre- and post-procedure). 7.Incidence of complications within 30 days. 8.Recurrence rate within 3 months. 9.Presence, pattern, and reversibility of atrioventricular (AV) conduction disturbances leading to cryoablation termination at the LVV-identified target region (hot-spot). | — |
Countries
Japan
Contacts
Public ContactYoshitake Oshima
Gifu Prefectural General Medical Center Cardiology
Outcome results
None listed