Adult patients(over 18 years old) admitted to the intensive care unit (ICU)
Conditions
Interventions
Intervention period: January 1 2022 December 31 2023 (Old nutrition protocol group approximately 200 patients) January 1 2024 December 31 2025 (New nutrition protocol group approximately 100 patient
Sponsors
Tohoku University Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Diagnosis: all eligible ICU cases Disease stage: all stages included Age over 18 years at enrollment All sexes included Patients admitted to the ICU during the study period
Exclusion criteria
Exclusion criteria: Patients deemed unsuitable for the nutrition protocol by the attending physician Patients with DNAR orders or those receiving palliative treatment Patients under 18 years of age
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Data extracted from medical records will include Patient characteristics age sex height weight (BMI) admission diagnosis and main ICU condition (e.g. trauma sepsis postoperative management). Severity indicators: APACHE II and SOFA scores at ICU admission. Clinical course: ICU admission/discharge dates, duration of mechanical ventilation, types and duration of sedatives, anesthetics, and opioids (as potential factors affecting gut motility). Nutrition management: day of enteral nutrition initiation (days from ICU admission) route of administration (nasogastric nasojejunal etc.) type of formula (product name fiber content) and use of parenteral nutrition. Nutritional intake: daily enteral feeding rate volume (mL/day) caloric intake (kcal/day) and protein intake (g/day) including interruptions and reasons. Gastrointestinal symptoms: daily bowel movements stool consistency (including Bristol scale scores) vomiting events (frequency and content) and gastric residual volume. Calculated variables: Required energy/protein: estimated using institutional protocols or established formulas. Cumulative intake: total energy and protein administered via enteral and parenteral routes. Nutritional adequacy rate: percentage of actual intake vs. requirement evaluated for the first 7 days and overall ICU stay. Time to first defecation: days from ICU admission to first bowel movement (constipation defined as >3 days without defecation). Days with diarrhea: frequency and duration of diarrhea episodes. Time to onset of GI symptoms: interval between enteral nutrition initiation and occurrence of vomiting or abdominal distension. | — |
Countries
Japan
Contacts
Public Contactmasaki abe
Tohoku University Hospital ICU
Outcome results
None listed