esophageal cancer, esophagogastric junction cancer
Conditions
Interventions
None listed
Sponsors
Gifu University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Patients who meet any of the following criteria will be included: Patients with cervical, thoracic, or abdominal esophageal cancer, or esophagogastric junction cancer, who have a history of gastrectomy (regardless of whether the previous gastrectomy was for benign or malignant disease) and underwent curative resection with non-gastric conduit reconstruction (using colon or small intestine), either as a one-stage or staged procedure. Patients with esophagogastric junction cancer requiring total esophagectomy and gastrectomy (or proximal gastrectomy) who underwent curative resection with non-gastric conduit reconstruction (using colon or small intestine), either as a one-stage or staged procedure. Patients with double cancer involving the cervical, thoracic, or abdominal esophagus and stomach, requiring total esophagectomy and gastrectomy (or proximal gastrectomy), who underwent curative resection with non-gastric conduit reconstruction (using colon or small intestine), either as a one-stage or staged procedure. Cases of esophageal cancer with gastric invasion and gastric cancer with esophageal invasion will be handled in the same manner. Patients who underwent curative resection with non-gastric conduit reconstruction (using colon or small intestine), either as a one-stage or staged procedure, due to intraoperative complications (e.g., intraoperative gastric conduit necrosis). Among the above, eligible patients are those aged 18 years or older who underwent surgery between January 1, 2013, and December 31, 2023.
Exclusion criteria
Exclusion criteria: Patients who underwent non-gastric conduit reconstruction as a reoperation due to postoperative complications (e.g., anastomotic leakage, gastric conduit necrosis, tracheal fistula, or refractory reflux esophagitis). Patients who underwent non-gastric conduit reconstruction following curative resection due to local recurrence of a prior disease or other related conditions. Patients who underwent non-gastric conduit reconstruction for metachronous double cancer, such as gastric conduit cancer. Patients who declined participation in this study through the optout process. Patients deemed inappropriate for inclusion by the attending physician's judgment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative weight loss rate Definition: The weight loss rate is defined as follows. Weight loss rate at X years after reconstruction = (Body weight at X years after reconstruction - Preoperative body weight) / Preoperative body weight | — |
Secondary
| Measure | Time frame |
|---|---|
| Reduction rate of psoas muscle area, reduction rate of BMI Nutritional indicators (PNI, NLR, PLR) PNI: Prognostic Nutrition Index NLR: Neutrophil-to-Lymphocyte Ratio PLR: Platelet-to-Lymphocyte Ratio Overall survival, relapse-free survival, progression-free survival Intraoperative complication rate, postoperative complication rate, curative resection rate | — |
Countries
Japan
Contacts
Public ContactYuta Sato
Gifu University Hospital Department of Gastrointestinal Surgery and Pediatric Surgery
Outcome results
None listed