Multicenter Cohort Study of Oncological Outcomes and Prognosis for Urothelial Carcinoma Treated by Chemotherapy in Ehime Prefecture

Multicenter Cohort Study of Oncological Outcomes and Prognosis for Urothelial Carcinoma Treated by Chemotherapy in Ehime Prefecture - Urothelial Carcinoma Treated by Chemotherapy

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000059620

Enrollment

400

Registered

2026-01-01

Start date

2026-01-10

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Urotherial carcinoma

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Episode 1 (Data update only): The study will include patients with unresectable or metastatic urothelial carcinoma who received chemotherapy from December 1, 2017, to June 30, 2024, at institutions within the Ehime Prefecture Urological Society. Episode 2: Patients of unresectable or metastatic urothelial carcinoma treated with chemotherapy between July 1, 2024, and December 31, 2026.

Exclusion criteria

Exclusion criteria: As this is an observational study, no specific exclusion criteria are stipulated.

Design outcomes

Primary

Measure	Time frame
Progression-free survival (PFS) and overall survival (OS) for each treatment, and prognostic factors.	—

Secondary

Measure	Time frame
Objective response rate (ORR), best overall response (BOR) and disease control rate (DCR) for each treatment. Safety, including treatment-related adverse events. Furthermore, detailed data on adverse events related to avelumab will be collected. Subgroup analyses based on histologic classification (e.g., predominant urothelial carcinoma vs non-predominant or non-pure UC)	—

Countries

Japan

Contacts

Public ContactKATSUYOSHI HASHINE

NHO Shikoku Cancer Center Department of Urology

hashine.katsuyoshi.vc@mail.hosp.go.jp089-999-1111

Outcome results