Comparative Evaluation of the Effect of UV Photofunctionalization and i-PRF Biofunctionalization on Osseointegration of Dental Implants: A Clinical and Radiographic Study

Comparative Evaluation of the Effect of UV Photofunctionalization and i-PRF Biofunctionalization on Osseointegration of Dental Implants: A Clinical and Radiographic Study - Comparative Evaluation of the Effect of UV Photofunctionalization and i-PRF Biofunctionalization on Osseointegration of Dental Implants: A Clinical and Radiographic Study

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000059615

Enrollment

Registered

2025-11-01

Start date

2025-11-02

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dental implants have become a reliable solution for restoring missing teeth, with long-term success largely dependent on achieving and maintaining osseointegration. Despite the high success rates reported, implant failures are still observed, commonly due to inadequate osseointegration or peri-implant infections. To improve outcomes, various surface modification strategies have been developed. UV treatment enhances protein adsorption, osteoblast attachment, and bone formation, thereby accelerati

Interventions

UV PHOTOFUNCTIONALISATION TO ENHANCE OSSEOINTEGRATION FOR DENTAL IMPLANT PLACEMENT i-PRF BIOFUNCTIONALISATION TO ENHANCE OSSEOINTEGRATION FOR DENTAL IMPLANT PLACEMENT

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Subjects more than 18 years 2. Able to provide consent 3. Presence of healthy periodontium in adjacent teeth 4. Presence of D2 or D3 quality of bone 5. Minimum 1.5 mm bone must remain between dental implant and neighboring teeth as well as on facial side, and 0.5 mm bone must remain between implant and palatal side

Exclusion criteria

Exclusion criteria: 1. Systemic diseases or metabolic disorders if any which may impact study, pregnant and lactating women. 2. Current smoker or quitted smoking <1 year ago 3. Parafunctional activities 4. Uncontrolled periodontal disease, caries, or clinical or radiographic signs of infection within two adjacent teeth 5. Current chemotherapy/radiotherapy or drugs that interfere with study.

Design outcomes

Primary

Measure	Time frame
To evaluate clinical parameters such as Implant Stability Quotient in the 2 experimental groups.	—

Secondary

Measure	Time frame
To evaluate radiographic parameters such as Bone Quality and Peri-implant Marginal Bone loss, Pink esthetic score and success and survival rate in the 2 experimental groups. To compare the data from the 2 groups and determine which functionalization method, (UV photofunctionalization or i-PRF biofunctionalization) provides superior osseointegration and overall implant success.	—

Countries

Asia(except Japan)

Contacts

Public ContactAJAY P

CSI COLLEGE OF DENTAL SCIENCES AND RESEARCH DEPARTMENT OF PERIODONTICS AND IMPLANT DENTISTRY

drajaypraba05@gmail.com+916380099580

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026