Healthy adult volunteers under alcohol exposure
Conditions
Interventions
Participants are healthy adults (>
19 years old) who undergo baseline assessment in a sober state, including questionnaires on drinking habits and addiction screening, vital signs, and motor task performance. Each participant then cons
Sponsors
Institute of Science Tokyo
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Age > 19 years at the time of consent. Able to provide written informed consent for study participation. Habitual alcohol consumption of at least once per month under usual conditions.
Exclusion criteria
Exclusion criteria: History of trauma to the upper limbs or cervical spine Presence of neuromuscular disease, peripheral neuropathy, or any condition that affects finger motor function Severe alcohol use disorder/ alcohol dependence, past history of alcohol abuse, or screening positive for dependence or suspected dependence on an alcohol dependence screening questionnaire Pregnancy or breastfeeding Ongoing psychiatric treatment, or continuous use of psychotropic medication (e.g., antipsychotics, benzodiazepines) Hepatic dysfunction, or a history of diseases or pharmacological treatments that substantially affect alcohol metabolism Inability to rest on the morning following the experimental session Deemed unsuitable for participation by the principal investigator or subinvestigators
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change in kinematic parameters of finger motion obtained from the smartphone-based handwriting task and thumb-movement task, including handwriting pressure, handwriting speed, variability, time to touch, and swipe speed | — |
Secondary
| Measure | Time frame |
|---|---|
| Subjective intoxication scale score (every 30 minutes) Breath alcohol concentration (every 30 minutes) Blood pressure and peripheral oxygen saturation (SpO2) over time Total alcohol intake at the end of the experiment | — |
Countries
Japan
Contacts
Public ContactTomoyuki Kuroiwa
Graduate School of Medical and Dental Sciences, Institute of Science Tokyo Department of Orthopaedic and Spinal Surgery
Outcome results
None listed