Healthy individuals
Conditions
Interventions
In Group 1, the first intervention is conducted under the sleep fragmentation condition, forced awakening approximately every hour for 3-5 minutes during nighttime sleep. An interval of at least 7 day
Sponsors
National Center of Neurology and Psychiatry
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1)Female participants who regularly monitor their menstrual cycle and are available during the follicular phase 2)Individuals from whom written informed consent can be obtained
Exclusion criteria
Exclusion criteria: 1)Individuals with conditions likely to be exacerbated by experimental stressors, including insomnia (self-reported) 2)Individuals with arrhythmia, pacemaker implantation, or heart disease 3)Individuals taking medications that affect the autonomic nervous system function (such as beta-blockers, antidepressants, or steroids) 4)Individuals taking sleeping pills or other medications that affect sleep 5)Individuals deemed unsuitable at the discretion of the principal investigator
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Heart rate variability | — |
Secondary
| Measure | Time frame |
|---|---|
| Other autonomic nervous system functions, as well as attention, cognitive, and emotional functions, the endocrine system, and the inflammatory response. | — |
Countries
Japan
Contacts
Public ContactKentaro Nagao
National Institute of Mental Health, National Center of Neurology and Psychiatry Department of Sleep-Wake Disorders
Outcome results
None listed