Healthy adults
Conditions
Interventions
None listed
Sponsors
FANCL Corporation
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: P: Participant The subjects were healthy adults (those who are not suffering from any diseases, excluding those under 18 years old, pregnant women, and lactating women). I: Intervention (food) characteristics Continuous intake of gamma-aminobutyric acid (GABA), Unlimited dosage forms, shapes and amounts. C: Comparison group Placebo or a similar food that did not contain gamma-aminobutyric acid (GABA). O: Evaluation items Main outcomes: Brain waves, heart rate variability, stress-related substances in saliva (cortisol, alpha-amylase, chromogranin A) Secondary outcomes: subjective evaluation (POMS, VAS, etc) In this SR, we will use the value at the time of assessment provided in each document, unless otherwise specified or unknown, in order to avoid multiplicity issues, we will use the value at the time of the last intervention. Furthermore, if a single study had multiple assessment time points, results from all reported assessment time points were used. S: Research design The research designs used in the literature were randomized parallel group controlled trials (RCTPs), randomized crossover trials (RCTCOs), and quasi-randomized controlled trials (quasi-RCTs). In addition, the languages of presentation were documents written in Japanese and English. As a general rule, the presentation format will be an original paper, and papers in the form of short reports or summaries will also be accepted if the content can be specified. Abstracts of academic conference presentations (conference minutes) were excluded because their descriptive content was considered insufficient. There was no question as to whether or not the journal in which the article was published had been peer-reviewed. To avoid publication bias, we also included studies with results published in clinical trial registry databases. Regarding gray literature, we decided to use doctoral theses, reports from government agencies, think tanks, etc. whose detailed contents could be identified.
Exclusion criteria
Exclusion criteria: The literature which does not meet the key inclusion criteria will be excluded.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Temporary mental stress relief: EEG, heart rate variability, stress-related substances in saliva (cortisol, alpha amylase, chromogranin A) | — |
Secondary
| Measure | Time frame |
|---|---|
| subjective evaluation(POMS, VAS, etc) | — |
Countries
Japan
Contacts
Public ContactMasakazu Katsu
FANCL Corporation Functional Food Research Institute
Outcome results
None listed