High-risk conditions for orthostatic hypotension: neurological disorders, cardiovascular diseases, kidney failure, COPD, hypertension, diabetes mellitus, fragility fractures, and deconditioning.
Conditions
Interventions
No compression during the head-up tilt testing
No compression during the head-up tilt testing ->
Sponsors
Shinshu University
Tokyo Bay Rehabilitation Hospital Fujita Health University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Age between 65 and 90 years 2. Having one or more of the following diseases as a primary diagnosis or comorbidity: Neurological disorders (stroke, spinal cord injury, head trauma, brain/spinal cord tumor, neurodegenerative diseases, demyelinating diseases, peripheral autonomic neuropathy, etc.) Cardiovascular diseases (heart failure, atrial fibrillation, myocardial infarction, etc.) Kidney failure COPD Hypertension Diabetes mellitus Fragility fractures Deconditioning 3. At least one week has elapsed since hospital admission 4. Expected hospital stay of at least four weeks 5. Sufficient cognitive and language function to understand instructions for the experimental procedures 6. Able to provide written informed consent from the participant or a legally authorized representative for participation in this study
Exclusion criteria
Exclusion criteria: 1. Unable to perform a head-up tilt test due to joint contractures, pain, or other physical limitations 2. Currently undergoing or scheduled to begin treatment for osteoporosis 3. Presence of abdominal aortic aneurysm detected on abdominal screening at admission, history of thoracoabdominal surgery within the past 2 months, tube feeding, or gastrostomy 4. Presence of cardiac pacemaker, prosthetic joint, or other metallic implants 5. Unable to maintain standing position for at least 3 minutes even with a tilt table due to severe dizziness or syncope 6. Unable to measure blood pressure on the upper arm due to humeral fracture, post-mastectomy status, or other reasons 7. Unable to undergo abdominal compression due to skin injury, itching, or discomfort around the pelvic area 8. Restricted from mobilization or exercise per attending physician's order 9. Any other condition deemed inappropriate for study participation by the attending physician or principal investigator
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Systolic blood pressure | — |
Secondary
| Measure | Time frame |
|---|---|
| Diastolic blood pressure Mean arterial pressure Heart rate Stroke volume index Cardiac index Total peripheral resistance index Visual analogue scale score | — |
Countries
Japan
Contacts
Public ContactKazuaki Oyake
Shinshu University Department of Physical Therapy
Outcome results
None listed