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Evaluation of the Usefulness of Continuous Positive Airway Pressure (CPAP) during EBUS-GS Guided Transbronchial Biopsy for Pulmonary Lesions

Evaluation of the Usefulness of Continuous Positive Airway Pressure (CPAP) during EBUS-GS Guided Transbronchial Biopsy for Small Peripheral Pulmonary Lesions - CPAP in EBUS-GS Guided Biopsy for Small Peripheral Pulmonary Lesions

Status
Recruiting
Phases
Phase 2
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000059379
Enrollment
85
Registered
2025-10-14
Start date
2024-04-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Peripheral lung lesion

Interventions

We are planning to use continuous positive airway pressure (CPAP) to keep the airways open during bronchoscopy, in order to improve lesion access and increase the diagnostic yield for small peripheral

Sponsors

Fujita Health University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Patients who visit Fujita Health University Hospital and require a pathological diagnosis by bronchoscopy for a pulmonary nodule or opacity that meets all of the following criteria: Patients who have received a full explanation about this study, fully understood the contents, and have provided written informed consent of their own free will. Patients aged 20 years or older and younger than 90 years at the time of consent. Patients with a target lesion less than or equal to 2 cm in the longest diameter on chest CT. Patients who have undergone thin-slice chest CT (slice thickness less than 2 mm) prior to bronchoscopy.

Exclusion criteria

Exclusion criteria: Patients with an evident pneumothorax prior to the procedure. Patients with respiratory failure (PaO2 less than 60 torr). Patients whose systolic blood pressure is below 80 mmHg immediately before the start of bronchoscopy. Any other patients judged to be inappropriate for inclusion by the principal investigator or sub-investigators.

Design outcomes

Primary

MeasureTime frame
Diagnostic yield of bronchoscopic biopsy under CPAP for peripheral pulmonary lesions

Secondary

MeasureTime frame
Diagnostic yield of bronchoscopic biopsy under CPAP for peripheral pulmonary lesions with a negative CT bronchus sign.

Countries

Japan

Contacts

Public ContactKazuyoshi Imaizumi

Fujita Health University Department of Respiratory Medicine

jeanluc@fujita-hu.ac.jp09065740609

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026