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Comparison of circuit lifespan between polysulfone and cellulose triacetate membranes during continuous renal replacement therapy

Comparison of the effects of polysulfone and cellulose triacetate membranes on circuit lifespan in continuous renal replacement therapy: A non-randomized controlled trial - A non-randomized comparative study on circuit lifespan between polysulfone and cellulose triacetate membranes

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000059366
Enrollment
48
Registered
2025-10-11
Start date
2023-06-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

cute kidney injury (AKI) or chronic kidney disease (CKD), including end-stage renal disease (ESRD), requiring continuous renal replacement therapy (CRRT)

Interventions

For patients requiring CRRT, hemofilters with cellulose triacetate (CTA) membranes were used for the first and second day of treatment. For patients requiring CRRT, hemofilters with polysulfone (PS) m

Sponsors

Japanese Red Cross Osaka Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: The study population consisted of patients admitted to the intensive care unit of our hospital between June 2023 and September 2024, for whom the attending intensivist or primary physician determined that continuous renal replacement therapy (CRRT) was required.

Exclusion criteria

Exclusion criteria: Patients meeting any of the following criteria were excluded from the study: Presence of significant coagulation abnormalities due to hematologic disorders. Use of a hemofilter other than the assigned membrane material during the first or second CRRT session. Circuit clotting caused by prolonged troubleshooting, such as device malfunction or inadequate blood flow. Missing data regarding patient background or CRRT treatment conditions.

Design outcomes

Primary

MeasureTime frame
The primary endpoint of this study was the cumulative circuit survival rate at 48 hours, analyzed using the Kaplan-Meier method.

Countries

Japan

Contacts

Public Contacttaro shimomura

Japanese Red Cross Osaka Hospital Department of Clinical Engineering

taroumail1978@yahoo.co.jp0667745111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026