Feasibility and Efficacy of Intra-procedural Direct Current Cardioversion During Structural Heart Interventions in Patients With Atrial Fibrillation: A Prospective Study

Feasibility and Efficacy of Intra-procedural Direct Current Cardioversion During Structural Heart Interventions in Patients With Atrial Fibrillation: A Prospective Study - INTRA-DC study

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000059339

Enrollment

100

Registered

2025-10-08

Start date

2025-11-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Atrial fibrillation, aortic stenosis, mitral regurgitation

Interventions

Direct current cardioversion

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients with atrial fibrillation deemed suitable for TAVI or M-TEER by a local heart team and undergoing the procedure under general anesthesia

Exclusion criteria

Exclusion criteria: Patients who have paroxysmal atrial fibrillation and present with sinus rhythm during the procedure Patients who undergo TAVI or M-TEER under local anesthesia Patients with intracardiac thrombus Patients who are ineligible for direct current cardioversion for any reason

Design outcomes

Primary

Measure	Time frame
Success rate of cardioversion	—

Secondary

Measure	Time frame
Rate of sinus rate at follow-up, echocardiographic findings, composite clinical endpoint based on VARC3 criteria (mortality, stroke, myocardial infarction, major bleeding, pacemaker implantation, acute kidney injury, device-related surgery or intervention)	—

Countries

Japan

Contacts

Public ContactTetsu Tanaka

St. Marianna Unversity School of Medicine Department of Cardiology

tetsu.tanaka@marianna-u.ac.jp044-977-8111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026